2,4-Dinitrophenol also referred to as DNP, is an active compound that essentially disrupts normal cellular respiration. The other name for DNP is Dinitro, Nitrophen, Dinosan, and Dnoc. It reduces the efficiency of the metabolic process. This forces the body to break down larger-than-usual amounts of fat and carbohydrates to meet its energy needs.
This process increases metabolism by up to 50 percent. That means if you normally burn 2,000 calories a day, you will burn around 3,000 calories while taking DNP, and most of the fat loss occurs around the abdomen and hips.
Individuals using this substance can lose a great deal of weight – up to 1.5 kg a week – without dieting and exercising. However, a serious side effect of increasing metabolism has elevated body temperatures. This substance is found in some supplements targeted toward bodybuilders looking to burn fat while retaining muscle.
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Is DNP dangerous?
In 1938, the Food, Drug, and Cosmetic Act of 1938 [Ref], said this substance was unfit for human consumption. They stopped the sale of DNP due to the side effects such as liver failure, cataracts, and death. But its use for weight loss was not eliminated. It is usually advertised as a safe weight loss aid, but one of the risks is that it accelerates the metabolism to a dangerously fast level. Speeding up metabolism may help burn off fat, but it can trigger side effects such as vomiting, nausea, headaches, dizziness, irregular heartbeat, dehydration, excessive sweating and rapid breathing.
Although DNP can lead to rapid weight loss by increasing metabolism, safer alternatives are available.